This issue is a variant of Irredeemable (Boom! Studios, 2009 series) #4. There exist further variants.
Per indicia: Copyright  Boom! Studios. Printed in Canada.
Spokes' variant covers to #1-12 will spell out "Irredeemable". This cover features the first E. It was offered to retailers as a 1-in-10 incentive. A "negative" variant using this cover's art also exists, as indexed below.
This variant, exclusive to retailer A Comic Shop and limited to 500 copies, uses Spokes' art to Cover C in "negative".
This convention exclusive, limited to 500 copies, uses Cassaday's black-&-white art to Cover A.
The inside front cover has head shots of cast from previous issues and recap of story so far, plus logo, credits, and indicia set against negative red-&-black detail of #1's Cover A.
Story is untitled beyond series title. First line: "Tony and I first met 5.7 years ago."
Poe #1 and its 8-page preview in this issue are hyped with art from Covers A and B.
Eeight pages of the story from Poe #1 are excerpted.
Gagnon writes about Boom!'s international talent pool in "Tick... Tick... Tick..." column. Page also includes Boom! masthead, brief Q&A with Poe artist Kotz, and small repros of covers to upcoming releases.
Advanced Research Technologies' JETT is advertised on the inside back cover.
Swordsmith Assassin is advertised on the back cover with art from #1's Cover A.