Spider-Girl [also appears as May Parker]; Kaine; Darkdevil; Arthur Weadon; Maria Hill; Earthshaker; Mr. Abnormal; Killerwatt; Davida Kirby; Courtney Duran; Heather Noble; Brad Miller; Jimmy Yama; Mr. Slattery; Simone DeSantos; Gene Thompson; Moose Mansfield; Donna Mansfield; Arthur Mansfield; Peter Parker; Mary Jane Watson-Parker; Benjamin Richard Parker; Contessa Valentina Allegra deFontaine; S.H.I.E.L.D.; Carnage
Kaine has assembled another group of supervillains, and Agent Maria Hill wants the group to guard the mysterious Specimen 297. Spider-Girl stumbles upon the transfer of the Specimen, and the container holding it is broken in the ensuing battle. The Contessa reveals that Specimen 297 is really Carnage, now on the loose. .