The cover solicited in May 2010 for this issue (featuring Superman in Earth orbit looking at a picture) was not used.
There was some controversy when a version of this cover was provided on DC's The Source Blog on 2010-06-01, as the flag had more than 50 stars on it (Cassaday, being British, may not have noticed). The extra stars were eliminated from the final cover.
Story continued from the previous issue, and continues in the next issue.
Eddie talks about Superman/Batman #75. Appears on page 34 in this issue.
House ads for: Green Lantern: Emerald Warriors, Brightest Day teaser (2 pages), and Superman vs. Muhammad Ali statue. Appear in various places in this issue.
Total of 4 one-page and 2 two-page ads for: Even Looks Good with Tights (sneakers, Journeys/Converse), React (gum, Wm. Wrigley Jr. Company), Metroid Other M (2 pages, video game, Nintendo Wii), Our Cover... or Yours? - Hero Factory (2 pages, sweepstakes, Lego), Like Me or Don't (abovetheinfluence.com), and got milk? with Deron Williams (milk, America's Milk Processors). Appear in various places in this issue.