Spider-Man [Peter Parker]; GUESTS: Aunt May Parker; Vin Gonzales; Harry Osborn; Green Goblin [Norman Osborn]; Anti-Venom [Eddie Brock]; Ben Urich; Sally Floyd; Betty Brant; Lily Hollister; Thunderbolts [Songbird; Venom [Mac Gargan; also as Scorpion]; Bullseye; Radioactive Man]; VILLAIN: Freak
Peter discovers that the illegal immigrants have been undergoing medical experiments at Oscorp. Norman extracts material out of Gargan and runs the substance through the captured Freak, thus producing a strong new poison. Bullseye and Thunderbolt agents attack Spider-Man and end up blowing up Harry's coffee shop during the battle. Spidey quickly discovers how he is being tracked and turns the tables on Bullseye. Anti-Venom shows up to help Spider-Man track down Osborn. Norman, now in full Goblin regalia, provides Gargan with a new Scorpion costume complete with the new poison.