This issue is a variant of The Amazing Spider-Man (Marvel, 1999 series) #546. There exist further variants.
2nd print variant utilizes an interior spash page as the cover image.
Story explains the new Spider-Man norm after events of the "One More Day" storyline and is written by the four creative directors of the series known collectively as "Spidey's Brain Trust."
Replaces letters page and includes miniature cover art for next issue.