Part of the DC/Marvel mashed-up Amalgam universe. Challengers of the Fantastic is a mash-up of the Challengers of the Unknown and the Fantastic Four.
This issue has variants:
Sue "Ace" Storm; Reed "Prof" Richards; Johnny "Red" Storm; Senator Ben "Rocky" Grimm; Ivan Kragoff (Amalgam); Super-Apes (Amalgam); Bronze Tiger; Von Doom, Victor (Amalgam); Vykin The Black Bolt; Dream Crystal; Medusa Moonrider; Uatu, The Guardian; Multi-Masters; June Masters; Otto Octavius (Amalgam); The Silver Racer; Galactiac; Doctor Doomsday