Disambiguation: DC
First published in: 1952
Created by Robert Kanigher and Alex Toth.
Rex the Wonder Dog first appeared in Rex the Wonder Dog (DC, 1952 series) #1 (January-February 1952). He regained his vitality when he drank from the Fountain of Youth in DC Comics Presents (DC, 1978 series) #35 (July 1981).
Link: https://en.wikipedia.org/wiki/Rex_the_Wonder_Dog