Wolverine; Fantomex; Agent Zero [Maverick]; Chamber; Sentinels (villains); Malcolm Colcord (villain); Bot (villain); John Sublime (villain); Mesmero (villain); Madison Jeffries (villain); Sauron (cameo); Agent Brent Jackson (cameo); Rachel Summers (cameo flashback); Colossus (cameo flashback); Angel (cameo flashback); Nightcrawler (cameo flashback); Storm (cameo flashback); Kitty Pryde (cameo flashback); Blob (cameo flashback); Avalanche (cameo flashback); Pyro (cameo flashback); The Professor (cameo flashback); Dr. Cornelius (cameo flashback); Hines (cameo flashback); Sabretooth (cameo flashback); Deadpool (cameo flashback); Aurora (cameo flashback); Kane [Garrison Kane] (cameo flashback); Wildchild (cameo flashback)
Thirty years in the future, Wolverine is ducking Sentinels and wondering how the Days of Future Past scenario actually came to pass as the X-Men thought they had prevented it. In the present, Malcolm Colcord, former Weapon X director, is forcing Madison Jeffries to churn out Sentinels in a bid for ultimate power. Wolverine and Agent Zero keep Fantomex from killing Colcord's chief rival, John Sublime, but Chamber shows up to finish the job. When Wolvie confronts Chamber, he gets burned for his efforts.
Five years in the future, with John Sublime dead and with his Sentinel army growing, Colcord is firmly in control of the Weapon X program and sets his sights on the world. Six years in the future, Colcord uses Mesmero, Sauron and Wildchild to threaten the X-Men to draw out Wolverine. Despite Wolvie's best efforts, Colcord has his Sentinels destroy the X-Men but leaves a badly wounded Logan to recover and live with his failure. Things start to go wrong when the Sentinels also kill Mesmero and Wildchild, claiming that they are programmed to kill ALL mutants.
Agent Zero has a nightmare about being used as a sleeper agent for Brent Jackson and Weapon X. Thirteen years in the future, Wolverine gathers a new team of X-Men to battle Colcord and his Sentinel army. Nineteen years in the future, Agent Zero's worst nightmares come true as he finds he can't control his actions as he kills many of Logan's X-Men before killing himself. Colcord discovers that Wolverine is still alive and discusses the situation with his ally, Mastermold.
Twenty-nine years in the future, Colcord and his Sentinel army have a firm grip on the world and mutants are on the verge of extinction. Wolverine leads his X-Men to a gathering called by Magneto. Nimrod Sentinels lead the regular Sentinels straight to the mutants. Magneto destroys the killer robots and the mutants cheer him as their new leader. Wolverine and Magneto travel visit Earth's few remaining non-mutant heroes to ask for help. The heroes comply but are completely wiped out. Wolvie learns that this was all part of Magneto's plan to show the world that the Sentinels must be stopped.
Thirty years in the future, Mastermold is in control and his Sentinels are putting humans in internment camps. Wolverine and his allies break into Weapon X and rescue Rachel Summers. They plan on using her to send someone back to the past to save the future. Colcord decides not to stop the mutants. Rachel sends Logan back into his past so he can stop himself from carving up young Weapon X soldier Malcolm Colcord's face. Things go just as planned until Fantomex reveals to Rachel that he has been possessed for years by John Sublime who leaps into Logan and forces him to slice up Colcord.