- Script
- Peter David (credited)
- Pencils
- Rick Leonardi (credited)
- Inks
- Al Williamson (credited)
- Colors
- Steve Buccellato (credited)
- Letters
- Rick Parker (credited)
- Genre
- science fiction; superhero
- Characters
- Dana D'Angelo; Aaron Delgato; Lyla; Spider-Man [Miguel O'Hara] (Marvel 2099 - Earth-928); Tyler Stone
- Synopsis
- Miguel O'Hara, hot-shot geneticist, tries to quit his job at Alchemax but is addicted to a drug by his boss, Tyler Stone. In an effort to free himself of the addiction, his genetic code is merged with a spider's genetic code.
- Reprints
Origin of Spider-Man 2099 (Part one of three)
- Script
- Peter David (credited)
- Pencils
- Rick Leonardi (credited)
- Inks
- Al Williamson (credited)
- Colors
- Noelle Giddings (credited)
- Letters
- Rick Parker (credited)
- Genre
- science fiction; superhero
- Characters
- Aaron Delgato; Lyla; Gabriel O'Hara; Spider-Man [Miguel O'Hara] (Marvel 2099 - Earth-928); Tyler Stone; Venture
- Synopsis
- Miguel learns about his new powers as he escapes Alchemax. Tyler Stone sends Venture, a professional tracker, after whoever was in the lab. Rather than let Venture find out who he is, Miguel dresses up and attacks him as Spider-Man.
- Reprints
The origin of the Spider-Man 2099 costume.
- Script
- Peter David (credited)
- Pencils
- Rick Leonardi (credited)
- Inks
- Al Williamson (credited)
- Colors
- Noelle Giddings (credited)
- Letters
- Rick Parker (credited)
- Genre
- science fiction; superhero
- Characters
- Lyla; Gabriel O'Hara; Spider-Man [Miguel O'Hara] (Marvel 2099 - Earth-928); Tyler Stone; Venture; Thorites (guests, followers of Thor)
- Synopsis
- Miguel fights Venture after he kills a Thorite, then leads him on a merry chase, but is captured. He breaks free and finally defeats Venture. In the meantime, Gabriel figures out that Spider-Man is his brother.
- Reprints
In addition to talons on hands and feet that allow him to scale walls, Miguel learns that he also has super-strength and can shoot webbing from his forearms.