Distributed to newsstands in December 1961 (December 5 according to Joseph Marek's Marvel Comics Group history website, December 7 according to Bob Bailey). This issue includes 10 pages of paid advertisements.
This issue has variants:
Puzzled space explorers are unable to detect any signs of life in an entire galaxy. They set for home frustrated that no colonies can be established there, not realizing that all the planets of that particular galaxy are living beings.
A conceited jerk wins Mr. Earth and is contacted by aliens who wish him to enter a "Mister Universe" competition. He doesn't stop to ask what the prize is, but arrogantly accepts, figuring he can beat the other contestants even though they are even more bigger and muscle-bound than he is. It turns out the other contestants knew what the prize was and so they let the Earth representative win, as he is then turned into a living statue for all the universe to marvel at forever.