Part 1 of 3. 1st appearance of Madame Hydra. James Bond had faced a "Madame Spectra" in the 007 newspaper strip story "The Spy Who Loved Me" in THE DAILY EXPRESS (December 18, 1967-October 3, 1968); see JAMES BOND 007 # (Titan Books, August 2005). Last previous appearance of HYDRA in STRANGE TALES #159 (July 1967); its subsidiary, A.I.M., had effectively split off to become a separate organization and continued to crop up in the Nick Fury, Captain America & Iron Man series. Cap had first asked Rick to be his partner in THE AVENGERS #4 (March 1964), but kept hemming and hawing over it for almost 5 years! The sequence in the sewers is strikingly similar to the one in "Spy Ambush" in CAPTAIN AMERICA COMICS #10 (January 1942). The Spirit had also once faced a female villain who planned to poison NYC's water supply in an early story.