Gabriel's girlfriend, Kasey, is kidnapped by Alchemax so they can run experiments on her. When she escapes, The Specialist goes after her, and Miguel goes after The Specialist.
Fan letters from: Jim Feken, Mike Diamond, Jeff Haardt, Miguel Andre Jerez, and Peter Chiang. One line previews of next Spider-man 2099, Ravage 2099, Doom 2099, and Punisher 2099 issues.