Deadpool takes a job which involves breaking a woman out of the loony bin. He takes another job to kill the same woman in the same loony bin. Sneaking in using Weasel as cover, Deadpool is forced to fight Vamp who is working at the asylum. Vamp turns into Animus which confuses Deadpool hormonally. Reaching the subject of his rescue/murder attempt, things become clear as the subject turns out to be Typhoid Mary whose distinct personalities have each put out a contract, one for her release and one for her death.