Vril Dox arrives on Earth, pursued by three bounty hunters, in search of Supergirl, whom a subspace transmission with no apparent origin told him to seek out. When he says a trigger word, Supergirl burns the instructions for a device on a disc with her heat vision. Once constructed, the device allows a program created by Brainiac 5 in the 31st century to be transmitted directly into Vril Dox' brain so that Brainiac 5 can ensure that the House of Dox not end with Vril. Elsewhere, the Omega Men encounter Dox' old organization, L.E.G.I.O.N., now under someone else's control.