Features the Amazing Spider-Man Brand New Day Saga; Profiles on Anti-Venom, Blue Shield, Freak, Hammerhead, Jackpot, Menace, Mr. Negative, Harry Osborn, Ramrod, Scorpia, Stiletto, Dexter Bennett, Bookie, Carlie Cooper, Vincent Gonzalez, Lily Hollister, Ana Kraven, Overdrive, Paper Doll, Dr. Benjamin Rabin, Screwball, Squid, Wayep, Bobby Carr, Randall Crowne, Bill Hollister, Alan O'Neil. Interview with Marc Guggenheim and John Romita Jr. on Character Assassination. Illustrations by Chris Bachalo, Barry Kitson.